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**Special of the month **

Restylane

Restylane before               Restylane after

 

What is Restylane-L?

Restylane-L® is a crystal clear injectable gel composed of hyaluronic acid, a natural substance that already exists in the body. Restylane-L is non-animal based and free from animal protein. Allergy pretesting is not necessary. Restylane-L contains 0.3% lidocaine. The lidocaine in Restylane-L has been added to reduce the discomfort associated with the treatment.

How does Restylane-L work?

Restylane-L is injected into the skin with an ultrafine needle to plump the skin to smooth away wrinkles and folds such as the lines from your nose to the corners of your mouth (nasolabial folds) or into your lips for patients over the age of 21 for lip enhancement.

Lidocaine was added to Restylane-L to reduce the pain and discomfort during and after injection.

In a clinical study, 60 patients received Restylane® on one side of the face and Restylane-L® on the other side of the face. Restylane-L had an effect on reducing pain. At the time of injection, patients rated their pain about 45 on a scale of 0 to 100 for the side of the face treated with Restylane. In comparison, patients rated their pain about 15 on the same scale for the side of the face treated with Restylane-L. Patients reported less pain on the side of the face treated with Restylane-L up to 60 minutes after treatment.

How long does Restylane-L last?

Restylane-L effects generally last about six months and gradually disappears from the body.

Has Restylane-L been studied?

A clinical study was conducted with Restylane-L to evaluate the pain reducing effect up to 60 minutes after injection. This study enrolled 60 patients with moderate to severe nasolabial fold wrinkles. The study included 58 female patients and 2 male; 34 were White, 21 were Hispanic or Latino, 3 were African American, 1 was Asian, and 1 was “Other”.

In this study 71.7% of patients experienced less pain after injection of Restylane-L than with Restylane alone. Please see the below table for additional information.

In addition to evaluating the pain reducing effects, the study assessed patient satisfaction with Restylane-L treatment. All 60 subjects were asked to rate the level of improvement seen in their nasolabial folds after injection with Restylane-L. At day fourteen after injection 100% saw some improvement (Improved, Much Improved, and Very Much Improved).

Who should not use Restylane-L (Contraindications)?

Safety has not been established and should not be used in people who are:

  • Pregnant
  • Breast feeding
  • Trying to become pregnant
  • Under the age of 22 for lip enhancement
  • Under the age of 18 or over the age of 65
  • Highly allergic (for example: gram positive bacteria)
  • Prone to bleeding disorders

What are some warnings to consider?

The use of Restylane-L at sites with skin sores, pimples, rashes, hives, cysts, or infections should be postponed until healing is complete. Use of Restylane-L in these instances could delay healing or make your skin problems worse.

You may experience skin discoloration (bruising), swelling, redness, tenderness, pain, itching, or small lumps in the area where you are injected. If any of these events occur, the majority usually last one to two weeks. If any symptom lasts longer than two weeks, call the doctor who administered the Restylane-L injection.

Red or swollen small bumps (inflammatory papules) may rarely occur. You may need antibiotics to treat them.

In clinical studies swelling was higher in younger patients (28%) compared to older patients (18%) and bruising was higher in older patients (28%) compared to younger patients (14%). The majority of these events were mild.

If you are injected with Restylane-L into your lips, your physician should be able to feel the product when touching your lips.

*These are typical results, but results may vary and cannot be guaranteed.

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